The U.S. economy has never been more integrated with Canada and Mexico. The 25% tariffs that President Trump has said he would impose on America’s two largest trading partners on Tuesday could upend those relationships—and no sector is as exposed as the automotive industry.

Mexican President Claudia Sheinbaum says she hopes to speak with U.S. President Donald Trump now that he has announced plans to impose tariffs on Mexico and Canada starting Tuesday.

President Donald Trump said Thursday tariffs of 25% on Mexican and Canadian goods are set to take effect on March 4, while also threatening to impose an additional 10% on Chinese imports on the same date.