Recent studies point to the adipose tissue as a highly active endocrine organ secreting a range of hormones. There is great interest in clarifying the role of adipose tissue-derived peptides ...

Diabetes has become a leading cause of morbidity and mortality and the prevention and management of diabetes is now a major global health concern. While recent studies link obesity with diabetes, ...

Researchers investigated the role between adiponectin and leptin in obesity-related carcinogenesis. Their findings suggest that the protein hormone adiponectin has potential for inhibiting the ...

While obesity is a well-known cause of cardiovascular disease, research from Sweden has now revealed that one of the body's obesity-related hormones -- adiponectin -- is also linked to osteoporosis ...

Adiponectin, a hormone secreted by adipose tissue, plays a doubly important role in preserving pancreatic function: in lean people, it protects beta cells, which make insulin, and in obese people, it ...

The fat-generated hormone adiponectin plays an important role in the energetic capacity of skeletal muscle, according to a new study in the July, 2006, Cell Metabolism, published by Cell Press.

Fig 1. Possible pathways by which adiponectin exerts either inhibitory (blue) or stimulatory (gold) modulation that ultimately results in cell- and tissue-level effects that potentially reduce risk ...

Stimulating the body’s immune defenses against a tumor can reduce or eliminate it. However, in cancer immunotherapy, when immune checkpoint inhibitors unleash the immune system, severe autoimmunity ...