Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...
Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.
Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process.
Researchers from North Carolina State University and Johns Hopkins University have demonstrated a technology capable of a suite of data storage and computing functions—repeatedly storing, retrieving, ...
DNA repair systems have evolved to rectify exogenous or endogenous DNA lesions. FAN1 (FANCD2/FANCI associated nuclease 1) 1,2,3,4,5 is a DNA repair enzyme involved in removal of extrahelical ...
PARP1 detection of DNA strand breaks allosterically leads to PARP1 synthesis of poly(ADP-ribose) modifications that signal DNA damage. HPF1 engages activated PARP1 to control modification site ...