Individual genes express multiple mRNAs by pre-mRNA alternative splicing, alternative polyadenylation or use of alternative promoters (first exons). As a result, individual genes express multiple ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -- single-stranded RNAs involved in protein synthesis -- and proteins from the same stretch of DNA, ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays ...

What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent PhD graduate Dr. April Lo from Dr. Alice Berger’s Lab ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation. As a core member of ...

Patterns of alternative splicing of mRNA differ between tumors and the normal tissues from which they are derived. 2 It has been recognized for some time that aberrant splicing may produce neoantigens ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

The initial report of phase I trial of VG2025, a non-attenuated HSV-1 oncolytic virus expressing IL-12 and IL-15/RA payloads, in patients with advanced solid tumors. This is an ASCO Meeting Abstract ...