A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in ...

Elaine Bearer sits at a wraparound desk with several computers, notebooks, and laboratory supplies strewn about. A confocal microscope about the size of a desktop computer from the 1990s sits in front ...

In Alzheimer’s disease, amyloid-β peptides and tau proteins assemble into filaments that are thought to be harmful to the brain. Amyloid-β filaments clump together in the space between brain cells and ...

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue ...

In-vivo imaging of the neuronal activity in mouse primary visual cortex. Left, high-resolution neuronal map; middle, high-speed neuronal activity recording captured by the two-photon microscope with ...