Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have ...
Scientists have addressed a long-standing controversy behind the molecular players mediating calcium signaling, a biological process that coordinates a wide array of physiological responses, according ...
Researchers at the University Medical Center Göttingen (UMG) have shown how a minimal change in a single ion channel increases the sensitivity of sensory cells in the inner ear. Even soft sounds, such ...
When three bright minds from different disciplines come together, something exceptional can happen. This is exactly what Prof. Patricia Hidalgo, Dr. Beatrix Santiago-Schübel, and Dr. Mercedes ...
Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have ...
Calcium channel blocker (CCB) overdose presents as profound hypotension, bradycardia and, in severe cases, cardiogenic shock. The principal mechanism involves impaired calcium influx into cardiac and ...
A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an ...
Lysosome malfunction caused by an organelle's inability to clear lipids or other waste from the cell plays a central role in lysosomal storage diseases (LSDs). Though those diseases have disparate ...
An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study. Targeting this protein -- the ORAI1 calcium ...
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