New research identifies calcium as a key chemical signal within brain immune cells that regulates anxiety-related behaviors ...

Researchers had previously discovered a population of immune cells within the brain that can act as accelerators and brakes ...

Cerebral blood delivery depends on mechanisms such as electrical signaling, which propagates through capillary networks to upstream arterioles to deliver blood, and calcium signaling, which fine-tunes ...

High calcium levels in brain microglia are linked to anxiety, suggesting new treatment possibilities for neuropsychiatric disorders. Research from the University of Utah highlights calcium as a key ...

Mitochondrial calcium signalling plays a fundamental role in cellular homeostasis by modulating energy production and activating key metabolic enzymes. Calcium ions (Ca2+) are dynamically exchanged ...

Calcium signalling represents a fundamental process in cellular communication, orchestrating diverse physiological responses from muscle contraction to neurotransmission and gene regulation. At the ...

In a sharp and pointy world, wound healing is a critical and marvelous process. Despite a tremendous amount of scientific study, many outstanding mysteries still surround the way in which cells in ...

The single-celled Stentor coeruleus learns through CaMKII-driven protein modification, mirroring mechanisms found in the human brain.

This influx of calcium at the contact site attracts and activates a kinase called CaMKII, a protein known to be important in memory. CaMKII alters the plasma membrane's biochemical properties, ...

Researchers from the University of Utah have identified calcium as a key chemical signal that triggers microglia during ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

Exemplary Ca2+ signaling microdomains. Cartoon illustration of various microdomains featured in different types of cells, all being artificially integrated in a hypothetical single cell. (1) Cardiac ...