Osaka, Japan - Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also ...
Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also discovered the ...
The sarcomere is the most basic contractile unit in skeletal and cardiac muscle. Mutations in genes encoding sarcomeric proteins give rise to heritable myopathies, although muscle function is more ...
When a muscle contracts, the parts of a sarcomere "shorten" and come closer together. Each cardiac muscle cell can have over 5,000 sarcomeres, which compounds both the shortening and relaxation events ...
Researchers have investigated the effect of increased cell temperature on the contractility of skeletal muscle and cardiac muscle by heating the muscle proteins using advanced microscopical techniques ...
L-type Ca²⁺ currents determine the shape of cardiac action potentials (AP) and the magnitude of the myoplasmic Ca²⁺ signal, which regulates the contraction force. The auxiliary Ca²⁺ channel subunits ...
Researchers have identified a novel mechanosensitive regulation of epithelial tube contraction. Many of the fundamental processes of life rely on biological structures known as epithelial tubes. These ...
Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...
The paper by Parmley et al. in this issue calls attention to the possible therapeutic use of glucagon in view of its possible inotropic and chronotropic effects in man. Such effects have previously ...
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