In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers at the University of Basel have now discovered that these skeletal cells do not just ...

Perlecan is a large heparan sulphate proteoglycan integral to the assembly, maintenance and mechanical responsiveness of cartilage. During embryonic and postnatal cartilage development, perlecan ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

Researchers in Sweden have engineered a cell-free cartilage scaffold that can guide the body to rebuild damaged bone. By removing the cells but preserving the structure and natural growth signals, the ...

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...

Bone and skeletal injuries are a major cause of long-term disability around the world. In light of this medical need, Swedish scientists have engineered a cell-free cartilage scaffold that can guide ...

With funding from ARPA-H, three teams of researchers have regrown bone and cartilage, even entire knees, in animal studies. Human trials are not far off. By Gina Kolata Three years ago, a little-known ...