Inhibiting locus coeruleus input to the medial prefrontal cortex in mice impaired task performance, affected the tuning of single cortical neurons and disrupted population dynamics and encoding ...

2022 Neuropsychopharmacology Reviews: Prefrontal Cortex The prefrontal cortex (PFC) is essential for developing action plans, driven by the coordination of cognitive and emotional processes, that ...

Neuronal sequences in the medial prefrontal cortex of the brain encode critical information associated with a procedural rule. These sequences can be explored and leveraged as novel biomarkers for ...

In a new JNeurosci paper, a Boston College research team led by John Christianson explored how a pathway between two areas of ...

Much criminal behavior derives from logical, if not laudable, sources. A wonderful example of this was seen in the old Bob Newhart television show. Newhart, playing a clinical psychologist, leans ...

Researchers reveal that TMS repairs depression by regrowing dendritic spines on specific IT neurons in the prefrontal cortex.

Many horse owners think the existence of the prefrontal cortex is a major controversy in equine science. It’s not. It’s just an area that’s riddled with misinformation. Curiously, most people—horsey ...

A new Nature Neuroscience study reveals that the ventromedial prefrontal cortex regulates how the hippocampus links related memories, preventing false associations. Researchers used advanced imaging ...

The cerebral cortex is your brain’s outermost layer. It has a wrinkled appearance due to the grooves and folds that increase its surface area. Here, we look at the anatomy of the cerebral cortex and ...