Insulin-like growth factor-1 (IGF-1) inhibited N-acetylsphingosine (C2-ceramide)-induced HL-60 cell apoptosis via relieving oxidative damage. This inhibitory action of IGF-1 was blocked by a ...

Ceramide induces apoptotic cell death in a dose- and time-dependent manner in neuroblastoma SKN-SH cells. Pretreatment with caspase inhibitors blocks cell death, suggesting that a set of caspase ...

If you were to ask anyone here at HuffPost which product holds the greatest importance in their skin care routine, a well-performing and all-purpose face moisturizer would rank fairly high. Over the ...

This was a non-controlled (all participants treated), open label (parents of participants and study staff all knew the treatment status of all children), phase 1 study. The trial was registered with ...

The study finds that this biomarker can show which patients may develop heart disease even if they have no current blockage or elevated cholesterol levels. A class of lipids called ceramides could tip ...

Ceramides are lipid molecules that rise sharply in kidney tissue when the organs are under stress. High ceramide levels interfere with mitochondrial function inside kidney cells. Mitochondria provide ...

In a paper just published in the inaugural issue of the new journal, Alzheimer's & Dementia, Claudio Costantini, Rekha Kolasani, and Luigi Puglielli argue that the lipids ceramide and cholesterol may ...

The best-selling lipid in the world, often prominently featured on skin cream and shampoo labels, appears to also hold promise for Alzheimer's treatment, scientists say. A long version of waxy, ...

Adrian J Lowe; Mimi LK Tang; Shyamali C Dharmage; George Varigos; Della Forster; Lyle C Gurrin; Colin F Robertson; Michael J Abramson; Katrina J Allen; John Su Importantly, this study provided useful ...