Homologous recombination (HR) is central to the template-based repair of DNA double-strand breaks, maintaining genome integrity 1,2,3,4. A central reaction in HR is the strand exchange, in which the ...

Toehold-mediated strand displacement (TMSD) is extensively utilized in dynamic DNA nanotechnology and for a wide range of DNA or RNA-based reaction circuits. Investigation of TMSD kinetics typically ...

The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location ...

Scientists at TU Delft and the Max Planck Institute have made a new class of structurally adaptable 'mechanical' pores made from DNA that can transport molecules through cell membranes. These ...

The Polymerase Chain Reaction (PCR) is a technique for the amplification of DNA in vitro (this describes experiments with cells outside their normal environment). PCR amplifies DNA using complementary ...

DNA replication is the process by which a cell makes an identical copy of its DNA. This process is performed at the beginning of every cell division so that when the cell divides, each daughter cell ...