During the process of transcription, DNA is converted to RNA, a complex molecule that is able to carry genetic information outside of the cell's nucleus. This page guides you through the biochemical ...

Researchers at The Ohio University have uncovered the mechanism by which thymine and guanine, the most commonly mutated bases in DNA, become damaged. The study, which was recently published in the ...

This image illustrates the chemical structures of the five main nucleobases found in DNA and RNA. The pyrimidines, thymine (DNA), uracil (RNA), and cytosine are shown on top while the purines, adenine ...

Cytosine methylation at CpG dinucleotides produces m⁵CpG, an epigenetic modification that is important for transcriptional regulation and genomic stability in vertebrate cells. However, m⁵C ...

Anyone who studied a little genetics in high school has heard of adenine, thymine, guanine and cytosine -- the A, T, G and C that make up the DNA code. But those are not the whole story. The rise of ...

There are four bases: Adenine and Guanine (purines); Cytosine and Thymine (Pyrimidines). Purines have two carbon-nitrogen rings while pyrimidines have a single carbon-nitrogen ring. Thus, there are ...

Exposure to ionizing radiation leads to formation of covalent crosslinks between DNA and proteins. The nature, extent and site of the modifications are not well understood due to the difficulty in ...