Diabetes goes beyond just glucose control, and recent advancements in research are enhancing drug development for the disease.

Autoimmune diseases represent the second largest global disease market after cancer. The global market for autoimmune disease drugs was worth $132.3 billion in 2022, with its value projected to grow ...

Janus kinase (JAK) inhibitors, including baricitinib, block cytokine signaling and are effective disease-modifying treatments for several autoimmune diseases. Whether baricitinib preserves β-cell ...

Teplizumab, a humanized monoclonal antibody to CD3 on T cells, is approved by the Food and Drug Administration to delay the onset of clinical type 1 diabetes (stage 3) in patients 8 years of age or ...

Argentine scientists have identified a mechanism that allows pancreatic beta cells, which produce insulin, to become ...

Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...

Prior to the COVID-19 pandemic it may have been primarily researchers in labs and clinicians in intensive care units who were aware of a dangerous form of infection-triggered runaway inflammation ...

Physicians have long observed a mystifying phenomenon: After a bout of infection or an autoimmune disease flare-up, some people experience prolonged mood swings, emotional dysregulation, and changes ...