Phospholipase A2 (PLA2) enzymes are known to play a role in many inflammatory diseases, including asthma, arthritis and atherosclerosis. It then stands to reason that PLA2 inhibitors could represent a ...

Researchers at the University created an AI model called EZSpecificity to test how certain enzymes and substrates bind to ...

A team from the University of Illinois has developed a modeling framework connecting enzyme activity related to photosynthesis to yield. This is the first time a model has tied the dynamic ...

Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job. Now researchers at Chalmers University of Technology have developed a computer model ...

Supercomputers and models aided researchers in understanding enzymes that metabolize cocaine, potentially before molecules of the addictive drug hit the brain. And the use of models has helped ...

An enzyme-based treatment developed by Yale researchers mitigated autoimmunity and reduced death rates in both genetic and non-genetic mouse lupus models, a new study reveals. The findings, which were ...

Coupled oxygen transfer and electron transfer reactions that use cofactors are enzymatic reactions of crucial significance to all lifeforms from bacteria to vertebrates. In the European Journal of ...

Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and ...

TEHRAN (Tasnim) – To better understand PLA2 enzymes and help drive therapeutic drug development, researchers developed 3-D computer models that show exactly how two PLA2 enzymes extract their ...