Nuclear receptors (NRs) are ligand-activated transcription factors that have central roles in nearly every aspect of development and adult physiology 1. This family contains 48 members in humans.

MANITOBA, Calif.--(BUSINESS WIRE)--FXR Pro Fish, a brand driven by bringing innovation to the water, is proud to announce its partnership with the Bassmaster Elite series as the title sponsor for the ...

I have to admit, going through scores of customized Harley-Davidson motorcycles is a delight. Not only am I treated to incredible base machines, but I get to see them in the most diverse and ...

The systemic expression of the bile acid (BA) sensor farnesoid X receptor (FXR) has led to promising new therapies targeting cholesterol metabolism, triglyceride production, hepatic steatosis and ...

Harley-Davidson has had some impressive bikes in its catalog in its century-long run. The motorcycle manufacturer has some of the most successful motorcycles in history, from the Softail Fat-Boy and ...

Eli Lilly has acquired Organovo’s lead asset, a clinical FXR agonist designed to treat inflammatory bowel disease (IBD), in a deal worth up to $50 million in biobucks. Organovo’s stock skyrocketed 244 ...

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism. Bile acids are natural ligands of FXR, which bind to the ...

Ask most Harley riders what they're on and the chances are you'll hear a familiar model name — Street Glide, Road Glide, and the iconic Softail design. However, what all but the most ardent of ...

FXR selects Industrials stocks from the Russell 1000 Index with high growth or value scores, whichever is better. Its expense ratio is 0.60% and FXR has $1.97 billion in assets. Its tiered-weighting ...