Efforts to better understand how immune cells function hold the promise of providing information that might lead to improved clinical treatments. Writing in Nature, Zhang et al. 1 present results that ...

The major inhibitory amino acid transmitter within the mammalian central nervous system (CNS) is GABA. Largely all of the brain’s neurons respond to GABA, while approximately 20% use it as their ...

Gamma aminobutyric acid (GABA) is a naturally occurring amino acid that works as a neurotransmitter in your brain. GABA is considered an inhibitory neurotransmitter because it inhibits certain brain ...

People with the inherited disorder myotonic dystrophy (DM) often experience excessive daytime sleepiness and fatigue, as well as altered responses to anesthetics that can put them at risk for ...

F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have prepared and tested cyclopenta-thieno-diazepine derivatives acting as GABA-A receptor subunit α2β2γ1 positive allosteric modulators (PAMs). As ...

Researchers at the Indian Institute of Science and collaborators used cryo-EM to decode the molecular architecture of a transporter protein controlling the movement of gamma-aminobutyric acid (GABA).

Respirerx Pharmaceuticals Inc.’s lead GABA-A receptor potentiator, KRM-II-81, has advanced to the next level of evaluation within the National Institutes of Health (NIH) HEAL Initiative Preclinical ...

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas ...