Nature

Add-on effect of hydrochlorothiazide 12.5 mg in Japanese subjects with essential hypertension uncontrolled with losartan 50 mg and amlodipine 5 mg

Approximately 43 million people in Japan suffer from hypertension. 1 The majority require a combination of antihypertensive drugs to achieve adequate blood pressure (BP) control. A cross-sectional ...
The New England Journal of Medicine

Chlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events

In a pragmatic trial, we randomly assigned adults 65 years of age or older who were patients in the Department of Veterans Affairs health system and had been receiving hydrochlorothiazide at a daily ...
Nature

Comparison between the effects of hydrochlorothiazide and indapamide on the kidney in hypertensive patients inadequately controlled with losartan

Hypertension can cause heart, brain, kidney and artery damage, increasing the incidence of cardiovascular disease and death. The purpose of antihypertensive treatment is not only lowering the blood ...
11Alive

Potentially life-threatening blood pressure prescription mix-up leads to recall

One lot of blood pressure medication is being recalled after it was potentially mixed up with a drug that could be deadly to some heart patients. A shipment of Hydrochlorothiazide Tablets USP 12.5 mg ...
TCTMD

In High BP, Chlorthalidone and Hydrochlorothiazide Have Similar Impact on MACE

CHICAGO, IL—Chlorthalidone does not reduce major adverse cardiovascular events compared hydrochlorothiazide in older, predominantly male military veterans with hypertension, according to the ...