New York, NY - A toxin isolated from coral reefs has enabled US scientists to better understand exactly how the sodium/potassium ion pump works and may ultimately help them to design molecules to make ...

This is a preview. Log in through your library . PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, ...

Hemiplegia, the paralysis of one side of the body, is a clinical manifestation observed in various neurological disorders. In several cases, the underlying aetiology involves dysfunction of the Na+/K+ ...

Researchers applied functional and structural analyses to investigate what structural features of proton/potassium (H+/K+) pumps and sodium/potassium (Na+/K+) pumps lead them to regulate the passage ...

The structure of the sodium-potassium pump is presented in a schematic cell membrane. The extracellular space is situated above and the intracellular space below the figure. The left-hand side of the ...

Researchers have succeeded in identifying the mechanisms involved in what is known as the acid pump, which at the cellular level pumps acid into the stomach -- in some cases leading to gastric ulcers ...

A protocol has been developed for the separation of brush-border membrane (BBM) and basolateral membrane (BLM) fractions from the kidneys of the roach (Rutilus rutilus) and the Arctic char (Salvelinus ...

The Nobel laureate was the first to identify an enzyme moving material across the cell membrane. A series of rodent experiments showed that even with abundant food and water, personal space is ...

The figure shows the tunnel-like entry point to the binding sites of the sodium-potassium pump in the sodium-bound state. The three small sodium ions are bound inside the pump (violet spheres to the ...