Dr. Portenoy answers the question: 'Over-The-Counter Pain Relievers Harmful?' — -- Question: Can Over-The-Counter Pain Relievers Be Harmful, And Are They Safer Than Other Drugs (Narcotics)?

"OTC stands for 'over the counter,'" says Dr. Mandy Leonard, senior director of pharmacy clinical services at Cleveland ...

Over-the-counter (OTC) pain medications are generally safe and effective, but daily or long-term use isn’t recommended. Several factors, including drug side effects and your medical history, can ...

Dr. Portenoy answers the question: 'Over-The-Counter Pain Killers, Caffeine?' — -- Question: Why Do Some Over-The-Counter Pain Killers Contain Caffeine, And Is That A Good Thing? Answer: Another ...

This story was originally published on April 18, 2025, and has been updated. On Monday, President Trump announced that the Food and Drug Administration would be discouraging the use of acetaminophen ...

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Study finds widely prescribed opioid painkiller tramadol shows limited effectiveness for chronic pain while increasing risk ...

New research indicates tramadol offers minimal pain relief, lowering scores by less than one point on average. The drug ...

If you’ve ever walked away from a tough workout with the poise of an immortal gladiator, only to wake up two days later feeling like you’ve been run over by a horse-drawn chariot, you’ve experienced ...

More British women suffering from chronic pain are opting for medical cannabis after over-the-counter treatments failed to provide any relief. They are turning to the rapidly expanding private sector, ...

When hit with a headache or fever, people often reach for over-the-counter painkillers like acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs) as their first line of defense. Used ...