Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Quantitative phase imaging (QPI) has become a vital tool in bioimaging, offering precise measurements of wavefront distortion and, thus, of key cellular metabolism metrics, such as dry mass and ...

In a landmark achievement in biological imaging, researchers at the University of California, Berkeley and Biohub today announced the successful demonstration of the laser phase plate, a novel device ...

Quantitative phase microscopy (QPM) has emerged as a revolutionary tool, enabling label-free imaging of biological specimens without the need for disruptive dyes or stains 1. This technique preserves ...

Installed in a custom Titan Krios, the laser phase plate enhances motion correction, early‑frame recovery, and 3D classification and alignment.

A computer-assisted design schematic showing how an electron beam is routed within a microscope. After going through the sample, it crosses a bright cyan beam representing the laser beam. A schematic ...