Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

Quantitative phase imaging (QPI) applied to holographic microscopy harnesses coherent light interference to record both intensity and phase information, enabling label-free visualisation of ...

Researchers have introduced a solution to the problem of light-sheet fluorescence microscopy: novel illumination beams designed based on deep learning using a trainable phase mask. Their study ...

A new kind of microscope is giving scientists a way to watch life inside cells with a clarity that feels almost unfair. Instead of choosing between seeing big structures or tiny particles, researchers ...

(A) When a traditional Gaussian beam is used, diffraction causes the illumination beam to widen at the edges. (B) Joint optimization scheme. A network predicts the positions of beads in the focal ...