Nature

Clinical implications of genetic polymorphisms on stomach cancer drug therapy

Gastric cancer (GC) is the second leading cause of cancer-related death worldwide, although its incidence in many Western countries declined during the last decade. Chemotherapy is widely used to ...
ascopubs.org

Use of ERCC1 polymorphism and extreme drug resistance assay to predict overall non-small cell lung cancer survival and responsiveness to platinum-based chemotherapy agents

Detection of serum proteomic profile predictive for epidermal growth factor receptor tyrosine kinase inihibitors (EGFR-TKIs) in 1st line chemotherapy responders No significant financial relationships ...
ascopubs.org

Genomic polymorphisms of drug metabolisms associated with overall survival (OS) in advanced non-small cell lung cancer (NSCLC) treated with gemcitabine (GEM) or taxanes.

Evaluation of Kras mutations and angiogenic biomarkers in patients with advanced non-small cell lung cancer (NSCLC) receiving single-agent sorafenib (S). Background: Several polymorphisms on the genes ...
Monthly Prescribing Reference

Polymorphism in Estrogen Receptor α Linked to Back Pain

(HealthDay News) – For women with degenerative spondylolisthesis (DS), polymorphisms in the estrogen receptor α (ERα) are associated with back pain intensity, according to a study published in the ...