Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are regulated by the organism to control protein ...

Caltech scientists have developed a method driven by machine learning that allows them to accurately measure the mass of individual particles and molecules using complex nanoscale devices. The new ...

An illustration of an antibody disrupting the binding between a virus particle and a receptor on the edge of a membrane. A drug (orange) blocks the SARS-CoV-2 virus (gold sphere with white protruding ...

In a study published in Nature Methods, a research group led by Prof. YE Mingliang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences (CAS), collaborating with Prof. LUO ...

Learn how to verify research-grade peptide purity using HPLC, mass spectrometry, and Certificates of Analysis, plus the key ...

A new method could soon unlock the vast repository of biological information held in the proteins of ancient soft tissues. The findings could open up a new era for palaeobiological discovery. A new ...

Study demonstrates a new way to study flu-host interactions in their native context and with structural insight.

A new data-driven technique, called fingerprint mass spectrometry, provides a method for measuring the mass of individual proteins using nanoscale devices. Caltech scientists have developed a method ...