A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics. Many ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

In synthetic and structural biology, advances in artificial intelligence have led to an explosion of designing new proteins with specific functions, from antibodies to blood clotting agents, by using ...

Protein language models are artificial intelligence tools which help engineer proteins with useful properties, including ...

This year’s Lasker Basic Medical Research Award recognizes the contributions of Demis Hassabis and John Jumper for their invention of the AlphaFold artificial intelligence (AI) system, which predicts ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction. Researchers from Cleveland Clinic and IBM recently ...

Inside every human cell, proteins are constantly being tagged with small chemical modifications after they're produced. Known ...

Proteins are life’s molecular machines, built from amino acids whose sequences and side chains dictate their structure and function. From essential dietary amino acids to complex folding patterns, ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...