The SARS-CoV-2 virus is continuously evolving and structural changes to the virus may impact the efficacy of antibody therapies and vaccines. A study describes the structural and functional landscape ...
The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.
One in every three FDA-approved drugs targets a single superfamily of receptors dotting the surfaces of human cells. From beta blockers to antihistamines, these essential, life-saving medications ...
Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...
Lefkowitz started to trace cell receptors in 1968. Using radioactivity, he managed to unveil several receptors, including one for adrenalin, the β-adrenergic receptor. His team then extracted the ...
BUFFALO, N.Y. – Touch a hot plate and your hand flies back. While the response is almost instant, researchers are still working to better understand the molecular mechanisms behind these sensations of ...
This new technique for studying cell receptors could have sweeping implications for drug development
Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors. One in every three FDA-approved drugs targets a single ...
Fragile X syndrome (FXS) is the most common inherited form of intellectual disability. The cause, which has been well-studied, is the loss of fragile X mental retardation protein (FMRP)—a genetic ...
6don MSN
Why some breast cancers evade treatment: Protein secreted by T cells may explain resistant tumors
Up to 20% of hormone receptor-positive breast cancers don't respond to antiestrogen therapies. A study led by researchers at ...
Researchers found that individuals have distinct baseline levels of brain-derived proteins in cerebrospinal fluid, masking ...
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