The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.

This article takes a deep dive into the history of proteomics from the conception of the term “proteome” up to modern-day advances in bioinformatics and single-cell protein analysis.

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...

Protein sequencing presents different challenges than nucleic acid sequencing, meaning that proteomics has yet to benefit as much as genomics from the next-generation sequencing revolution. However, ...

In the workflow of AmproCode, each type of the selected residues on peptide or protein samples can be respectively modified by the DNA barcode, and the composition code which is the relative ratio of ...

Whether you’re interested in why a living system works as it does or the reasons it goes awry, proteins are a critical part of the molecular picture. The proteins circulating in a person’s plasma can ...

Protein barcodes are short, information- rich stretches of amino acids encoded by DNA sequences that can be added to the DNA sequences coding for proteins. Then, when protein barcode DNA and protein ...