Study reveals how an RNA enzyme drives the postnatal switch from glucose to fatty acids in heart cells, highlighting ketogenesis as essential for metabolism. Study: The tRNA methyltransferase Mettl1 ...

A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics ...

Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage. Through international collaboration, ...

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life. But the inner workings of this ...

The novel Cleavage High-throughput Assay (CHiTA) developed at Penn State provides a scarless method to characterize thousands of diverse small self-cleaving RNA enzymes, called twister ribozymes, in a ...

The new CRISPR platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold ...

An extremely small RNA molecule created by a University of Colorado team can catalyze a key reaction needed to synthesize proteins, the building blocks of life. The findings could be a substantial ...

Salk scientists engineered a right-handed RNA enzyme (bottom left) that can combine left-handed RNA fragments (bottom right) to create a mirror image of itself. The new left-handed RNA enzyme (top ...

Scientists at the University of Maryland, Baltimore County, have uncovered a crucial trick used by enteroviruses—the group behind diseases like polio, myocarditis, encephalitis, and even the common ...

The closest-ever detailed look at a key enzyme inside the virus that causes COVID-19 could lead to more effective treatment ...

Now, a pair of Scripps Research Institute scientists has taken a significant step toward answering that question. The scientists have synthesized for the first time RNA enzymes that can replicate ...