To function normally, nearly every cell in the human body relies on G-protein-coupled receptors (GPCRs) to receive and send ...

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send ...

Researchers discover that the GPR3 receptor acts as an immediate-early gene to jumpstart neuron and synapse development.

Blocking a signaling pathway in certain white blood cells may prevent clots from obstructing blood flow and causing CTEPH, per a new study.

The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor of the bHLH/PAS protein family. In this review, we explore the multifaceted roles of AHR in both health and disease, ...

Angela SpiveyTo function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals ...

Toll-like receptors (TLRs) are key mediators of innate immune responses, and their dysregulation contributes to inflammatory diseases. Dehydroandrographolide (DAG), a diterpene lactone from ...

Researchers say newly identified cholesterol control pathway is completely separate from anything targeted by existing drugs.

One of the most important mechanisms is receptor-mediated signaling. A peptide attaches to a specific receptor on the cell surface, which then activates intracellular proteins such as kinases or ...

FGF21 is primarily known as a metabolic hormone. A new study by researchers at Helmholtz Munich and Ludwig Maximilians ...

An international study led by a scientist at the University of Ottawa Faculty of Medicine is opening new frontiers in the ...

A research team at Kanazawa University, led by Professor Atsushi Mizokami, Associate Professor Koji Izumi and Specially ...