News Medical

Characterizing the spectrum of mitochondrial DNA deletion disease syndromes

Researchers from the Mitochondrial Medicine Program at Children's Hospital of Philadelphia (CHOP) have better characterized a spectrum of what were classically considered discrete mitochondrial DNA ...
News Medical

Bringing flexibility to Sanger sequencing and DNA-fragment analysis with the Spectrum Compact CE System

In this interview, News Med is talking to Gabriela Saldanha about DNA Fragmentation and Sanger Sequencing. What are Sanger sequencing and DNA-fragment analysis? Where are these analyses used? Sanger ...
EurekAlert!

Recognizing the evolution of clinical syndrome spectrum progression in individuals with single large-scale mitochondrial DNA deletion syndromes (SLSMDS))

Philadelphia, February 20, 2025 – Researchers from the Mitochondrial Medicine Program at Children’s Hospital of Philadelphia (CHOP) have better characterized a spectrum of what were classically ...
ascopubs.org

Cancer spectrum among Irish DNA mismatch repair gene mutation carriers.

Clinical significance of tumor budding in colorectal cancer. Randomized phase II study of erlotinib (ERL) in two different schedules with concomitant modified XELOX in the first-line treatment of ...