In a recent study under review at the Scientific Reports journal and currently posted to the Research Square* preprint server, researchers synthesized and evaluated the antitumoral (against several ...

Spirocyclic compounds, characterised by two or more rings sharing a single quaternary carbon centre, have emerged as pivotal scaffolds in drug discovery and natural product synthesis. Their rigid ...

Spiro motifs are compounds that have at least two molecular rings with only one common atom. They are ubiquitous in natural products and bioactive molecules, but despite their wide application in ...