The first successful public demonstration of the inhalational induction of anesthesia took place in the surgical amphitheater of Massachusetts General Hospital on October 16, 1846. The news spread ...

IN INFANTS and children the technic of induction of anesthesia demands careful consideration, if optimal results are to be obtained. The success of the induction depends upon several factors, one of ...

Inhaled anesthetic agents include nitrous oxide (the oldest of all anesthetics) and various halogenated agents: desflurane (halogenated solely with fluorine—halogenation increases potency and is ...

Cotton rats (Sigmodon hispidus) are widely used as animal models for infectious disease and immunological research. They emulate many aspects of human disease pathogenesis, and the introduction of ...

Despite decades of common use for surgeries of all kinds, the precise mechanism through which general anesthesia works on the body remains a mystery. New research investigated the common anesthetic ...

Intravenous (i.v.) anesthetics include etomidate, midazolam, propofol, thiopental, ketamine, and opioid agonists. The first four agents act by enhancing the activity of the inhibitory neurotransmitter ...