“Since the discovery of transplantation as a life-saving therapy for blood malignancies by Dr. E Donnall Thomas, there have been major advances that have significantly lowered the side effects and ...

Rheumatoid arthritis (RA) susceptibility is strongly influenced by genetic variations within the major histocompatibility ...

Although drug eruptions are often linked to the human leukocyte antigen (HLA), the mechanism of its involvement in presenting symptoms of the skin remains unclear. In a recent study, researchers used ...

Although medications can often help patients find a cure or respite from their condition, millions of people worldwide suffer from unpredictable drug toxicities every year. In particular, drug ...

This podcast comments on a large registry study evaluating the effect of ultra-high-resolution HLA typing on outcomes of unrelated donor transplantation. For patients who are potential candidates for ...

A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system – the HLA class II molecules – while accurately predicting how they display ...