Changes Clinical Practice: Based on this large trial, lithium alone or a lithium-valproate combination should be used as first-line maintenance treatment for bipolar affective disorder type I instead ...

July 25, 2011 — Lithium is more effective in treating episodes of bipolar disorder (BD) than valproate. However, there is little difference between the 2 agents in reducing suicidality in this patient ...

Hayes et al 12 conducted one of the most recent large studies to compare lithium with newer second-generation antipsychotics as maintenance monotherapy for bipolar disorder. The authors concluded that ...

Other effective medicines are available for epilepsy and bipolar disorder and valproate should only be used if these don’t work or aren’t suitable for an individual patient. Image Credit: Medicines ...

Uzedy administered once every 2 months is not recommended for the maintenance treatment of bipolar I disorder. The Food and Drug Administration (FDA) has approved Uzedy ® (risperidone extended-release ...

A second meta-analysis of antimanic treatments, conducted by Yildiz et al, 6 focused on direct comparisons of individual medications and on effects of classes of medication. Second-generation ...