Imaging live cells is key to reveal their inner workings, dynamics, and function. Current technological advances in confocal imaging can benefit from novel fluorescence labeling strategies and ...

Extracellular vesicles, or EVs, are tiny membrane-bound particles released by nearly all cells. They carry proteins, RNA, lipids, and other biological cargo that reflect the condition of their parent ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...

Prof. Fang-Jen S. Lee's team at National Taiwan University has discovered that an intermediate cellular metabolism molecule, glycerol, regulates the localization and function of the Golgi protein Imh1 ...

Video depiction of vesicle fusion and tethering. In the active zone in the central left of the video, docked vesicles (dark blue) fuse with the membrane, releasing their contents and being quickly ...

Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell ...

Scientists haven’t had a precise way to arrange and study surface-bound extracellular vesicles and particles (EVPs) as they guide cell behavior. Researchers developed LEVA, which uses patterned ...

A new study by researchers at Karolinska Institutet (KI) demonstrates how extracellular vesicles (EVs) activate the immune system in mice and seem to make their tumors sensitive to a checkpoint ...

Impaired mitophagy and the accumulation of damaged mitochondria are key drivers of endothelial cell (EC)dysfunction in ...

Scientists from The Hong Kong University of Science and Technology (HKUST) and The Hong Kong Polytechnic University (PolyU) have developed an in-vitro vesicle formation assay, shedding light on cargo ...