For decades scientists have recognized that human immunodeficiency virus (HIV) is a formidable viral pathogen. After years of probing work and extensive experimentation, a Yale research team has ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

Viral infection induces cytoskeleton remodeling into cage-like structure. Virus infection can cause severe rearrangement of the cytoskeleton, and all three kinds of cytoskeleton form a cage-like ...

Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

DNA replication in viral systems encompasses a remarkable variety of strategies that exploit or mimic cellular machinery. Small DNA viruses often encode a multifunctional helicase–primase complex that ...

Zika virus (ZIKV) is a mosquito-borne orthoflavivirus that can cause birth defects, including microcephaly, a condition in which head and brain size are significantly reduced at birth. The collective ...

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...