The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

As we age, the composition and function of proteins in the brain change, affecting how well our brain performs later in ...

New research has outlined how cancer cells tolerate chromosomal imbalance by boosting production of the proteins the missing ...

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most ...

Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and ...

A single iron-sulfur building block directly determines whether ribosomes—the protein factories of our cells—work smoothly or ...

Translation factors eIF1A and eIF5B are key repressors of an abnormal protein translation process linked to neurodegenerative ...

The internet is full of claims about a so-called “protein intake ceiling," the idea that your body can only absorb a limited amount of protein per meal. But absorption isn’t really the issue—it’s how ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...

Scientists have discovered how the amino acid leucine boosts the body’s energy production by protecting key mitochondrial ...