Due to the 4-hour maturation half-life of the Timer protein's blue-to-red chromophore, we can detect reactivated or recently silenced proviruses with high sensitivity using Timer fluorescence.

The human immunodeficiency virus (HIV) is a retrovirus that integrates into the human genome. This intact, integrated genome is referred to as a provirus and represents a latent or dormant form of the ...

Researchers have succeeded in developing a designer recombinase (Brec1) that is capable of specifically removing the provirus from infected cells of most primary HIV-1 isolates. Researchers at the ...

A team of researchers studying HIV have created a test that they say will allow clinicians and scientists to better track efforts to cure the disease. Most HIV drugs attack the active virus, which ...

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