Serotonin (5-HT) plays an important role in shaping brain network dynamics by regulating excitatory synaptic function and neuronal excitability. However, much less is known about how 5-HT tunes ...

RNAScope was used to confirm presence of Htr2a mRNA in prefrontal cortex (PFC) and anterior dorsal (AD) thalamus. RNAScope was also used to validate loss of Htr2a mRNA after viral transfection of Cre.

Researchers at Leipzig University's Carl Ludwig Institute have discovered that in the cerebral cortex, synaptic signal transmission between brain cells functions very reliably even at low ...

New research reveals how a class of neurons that help coordinate communication in the brain link up with their target cells, identifying two molecules that must be present before synapses, the ...

Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...