As rare disease trials face persistent feasibility challenges, Bayesian designs are gaining momentum by enabling more ...

In 2022, Rafael Nadal approached the baseline and began horizontally abducting his right arm to loft a tennis ball approximately 5 feet. He abruptly contacted the inferolateral aspect of the tennis ...

In a new draft guidance issued on January 14, 2026, the FDA discussed the use of a modern statistical methodology in clinical trials designed to show the effectiveness of a new drug. The guidance, ...

In today's ACT Brief, we explore how Bayesian approaches are powering studies in rare disease and pediatrics, a major public-private initiative is standardizing digital endpoints for regulatory ...

Pennington Biomedical Research Center hosted the NIDDK Clinical Methods for Nutrition and Obesity Research Course, an intensive four-day training program designed to equip postdoctoral fellows, ...

Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF. Visit NAP.edu/10766 to get more information about this ...

Decentralized clinical trials involve a combination of participant-centered design with innovative technologies. Decentralized clinical trials can either be fully remote or adopt a hybrid approach ...

The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...