First-in-human trial of CRISPR gene-editing therapy safely lowers cholesterol and triglycerides

In a 15-patient, Phase 1, first-in-human trial, a one-time CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol ...
News-Medical.Net

Using CRISPR-Cas9 to uncover and target the genetic basis of obesity

CRISPR-Cas9 is a promising approach for obesity therapy, targeting key genes involved in appetite regulation, metabolism, and fat storage. Preclinical studies showed strong metabolic benefits, ...

Phages with fully-synthetic DNA can be edited gene by gene

A team led by University of Pittsburgh's Graham Hatfull has developed a method to construct bacteriophages with entirely ...

Scientists have edited a gene that may reduce high cholesterol permanently

With a snip of a gene, doctors may one day permanently lower dangerously high cholesterol, possibly removing the need for ...
Precision Medicine Online

CRISPR Therapeutics' Gene-Editing Drug Cuts LDL Cholesterol, Triglycerides in Early Human Trial

CTX310 showed promising safety and efficacy in a small Phase I trial, according to data presented at the American Heart ...