Mismatch repair pathway is frequently dysregulated across cancer types, commonly represented by loss of MLH1 or MSH2 gene expression. Here the authors model MLH1 missense mutations from patients to ...
This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence ...
Hi there—I’m Debra Ellis, and I believe healing begins with connection, compassion, and a good dose of humor. With over 30 years of experience in behavioral health, social work, and clinical ...