That superhero is a gene called TP53, and for decades scientists have known it as the “guardian of the genome.” In a healthy cell, TP53 acts like both a brake and an emergency stop button. When DNA ...

Sjögren-Larsson syndrome (SLS) constitutes a rare genetic disorder manifesting as a complex neurocutaneous condition characterised by congenital ichthyosis, progressive neurological impairment and ...

The tiny Amazon molly (Poecilia formosa) has always fascinated researchers because, according to the rules of evolution, it shouldn't have survived as a species, let alone thrive as a species for over ...

People typically die from progressive supranuclear palsy within 7 to 10 years. There is currently no specialized treatment or effective screening for this neurodegenerative disease.

Learn about comparative gene expression studies in Alzheimer's disease and other conditions in Mayo Clinic's Precision Medicine in Neurodegeneration Lab.

The Amazon molly reproduces without sex. A genomic copy-and-paste trick called gene conversion may explain how it avoids evolutionary meltdown.

Statistics that quantify a person’s predisposition to diseases such as diabetes and cancer can be reverse-engineered to reveal the underlying genetic data, prompting privacy concerns ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

An international team of scientists headed by researchers at the University of Edinburgh, has created a complete map showing how hundreds of possible mutations in a key cancer gene, CTNNB1, influence ...

Autism spectrum disorder is complex; it presents differently in different patients, and the causes are still unclear, even though hundreds of small changes in gene sequences have been linked to an ...

OBJECTIVE: Venous thromboembolism could be manifested as deep venous thrombosis or pulmonary embolism. The aim of this study was to assess the impact of genetic risk factors including prothrombin ...

Research links variations in the gene GRIN2A to a higher risk of developing schizophrenia and other forms of mental illness. The GRIN2A gene regulates communication between neurons by producing the ...