BACKGROUND Erythromycin has been reported to have an inhibitory effect on chronic inflammatory airway disease and chronic infiltration of neutrophils into the airway. Bleomycin (BLM) often induces ...

1 David Read Laboratory, Department of Medicine, University of Sydney, NSW 2006, Australia 2 Department of Respiratory Medicine, Westmead Hospital, Westmead, NSW 2145, Australia Correspondence to: Dr ...

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Background: Oxidative stress is thought to have a major role in the pathogenesis of airway obstruction. A study was undertaken to determine whether subjects with low levels of antioxidants (serum ...

Introduction Despite the introduction of dedicated asthma services and targeted therapies, asthma exacerbations remain a common cause of hospital admission with significant utilisation of health care ...

8 Department of Environmental Medicine and Public Health, Section of Occupational Medicine, University of Padova, Italy 9 Departments of Medicine, Oncology and Radiology, Section of Respiratory ...

1 Department of Geriatric Medicine, Royal United Hospital Bath NHS Trust, Bath, UK 2 Department of Respiratory Medicine, Glenfield Hospital, Leicester, UK 3 Department of Respiratory Medicine, ...

Background Tissue factor pathway inhibitor (TFPI) attenuates intravascular coagulation, a function limited by its proteolysis. Airway inflammation in COPD is associated with protease activity and ...

Objective Anaesthesiology guidelines suggest that opioids worsen obstructive sleep apnoea (OSA) despite no randomised controlled trial evidence. We therefore conducted a randomised controlled trial to ...

DST/NRF Centre of Excellence in Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, ...

Background Haemodynamic measurements may be superior to the 6-min walk distance (6MWD) as outcome measures in pulmonary hypertension (PH) as they are directly linked to the mechanisms of disease and ...

1 Department of Pulmonary and Intensive Care Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands 2 Department of Biostatistics, Erasmus Medical Center Rotterdam Correspondence to: ...