Digital health interventions (DHIs) show promise for the treatment of mental health disorders. However, existing meta-analytical research is methodologically heterogeneous, with studies including a ...

Baseline and longitudinal plasma p-tau217 were associated with subsequent decline in global cognition, progression to dementia, and increased tau burden, whereas baseline p-tau217 and GFAP were ...

The field of cellular immunotherapy has undergone a profound transformation in recent years, with autologous chimeric antigen receptor (CAR) T-cell therapies emerging as the standard-of-care option ...

The US Environmental Protection Agency (EPA) plans to abandon landmark regulations limiting airborne mercury and greenhouse ...

Over the past decade, several novel immunotherapies have transformed the treatment landscape of relapsed or refractory B-cell acute lymphoblastic leukaemia. In the pivotal TOWER trial, blinatumomab—a ...

The administration of US President Donald Trump has launched a full-fledged assault on science and public health;1 its “flood the zone” strategy created chaos and initially overwhelmed potential ...

Physicians treating patients with Crohn's disease face a plethora of drug choices. Yet, overall rates of clinical response seem stable over time,1 suggesting the existence of a therapeutic ceiling ...

Our analysis reveals major infrastructure deficits in the Commonwealth, which could directly affect the availability of effective, efficient, equitable, and responsive screening, diagnosis, and ...

It was by far the most difficult phone call of my life. Absolutely nothing can prepare you for telling your mother that she ...

The relationship between hormone therapy (oestrogen with or without progestogen) and breast cancer risk has been widely ...

We read with great interest the Lancet Oncology Editorial1 calling for a coordinated global approach to address the growing ...

We read with great interest the published results of the RADIOSA trial by Giulia Marvaso and colleagues.1 This well designed ...