Mar 18, 2024 · The distinct biologic features of different hyperuricemia subtypes call for the development of tailored, subtype-dependent, genetics-based therapies for gout or hyperuricemia.

Sep 27, 2022 · Gout Pharmacotherapy in Cardiovascular Diseases This review examines the utility of current gout therapies in the treatment and prevention of cardiovascular disease, …

In a phase 2 trial, firsekibart — an IL-1 beta antibody — outperforms colchicine in preventing acute gout flares over 12 weeks in patients with gouty arthritis initiating urate-lowering therapy.

Oct 29, 2025 · An expert in gout clinical trials questions whether ethical considerations for such trials need updating to emphasize patient choice, dose alterations, and anti-inflammatory …

Oct 27, 2025 · The drug colchicine may reduce cardiovascular outcomes among patients with gout, based on a range of retrospective data that suggest improved outcomes and mechanistic …

Aug 18, 2025 · Patients with gout are more likely than matched control individuals to be prescribed chronic opioid therapy, a large cohort study shows.

Oct 27, 2025 · In patients with gout, a novel prediction tool that relies on weight and creatinine clearance successfully identified the dose of allopurinol required to achieve a serum urate …

Sep 20, 2024 · Patients have an increased risk for cardiovascular events in the first month after a gout diagnosis that appears related to inflammation. "First gout diagnosis was associated with …

4 days ago · As a clinician, you probably understand the pathophysiology of vitamin D deficiency well. But here are four things you may not know about the evolving role of this hormone in the …

Jul 11, 2025 · Respiratory syncytial virus (RSV) infections were associated with significantly increased risk for complications beyond pulmonology, including poor kidney outcomes and …