Proteomics analyses showed lower levels of several complement proteins in the blood of people with hypermobile Ehlers-Danlos syndrome compared to controls. Complement proteins are part of the innate immune system and help regulate inflammation and coordinate immune signaling. Immune dysregulation may be an important component to understanding hEDS. Check out the full study here: Griggs M, et al. Proteomic discoveries in hypermobile Ehlers-Danlos syndrome reveal insights into disease pathophysiol
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