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The Spicy MD. on Instagram: "The Henderson–Hasselbalch equation traces its roots to early 20th-century acid–base chemistry and physiology: in 1908, American physiologist Lawrence J. Henderson described how the bicarbonate buffer system in blood maintains pH by relating acidity to the ratio of carbonic acid and bicarbonate, laying a foundation for understanding respiratory and metabolic control of acid–base balance. A few years later, in 1916, Danish chemist Karl Albert Hasselbalch refined Hender
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