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mt.com
Batch Crystallization Optimization and Process Design
A well-designed batch crystallization process is one that can be scaled successfully to production scale - giving the desired crystal size distribution, yield, form and purity. Batch crystalliz...
Apr 17, 2024
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Deduction of Scale-up Equations for a Crystallization The batch crystallization of a biochemical resulted in virtually identical properties when conducted either at the laboratory scale (1 liter) or the plant scale (1000 liters). The lab crystallizer had an impeller of 3 cm diameter operating at 750 rpm, while the plant crystallizer had a 30 cm impeller with a speed of 77 rpm. What scale-up equations can be used to approximately characterize the scale-up of this crystallization? What property or
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